Preliminary observations in cortical excitability changes using transcranial magnetic stimulation (TMS), it’s correlation with diffusion tensor imaging (DTI) in subjects with neuromyelitis optica spectrum disorder (NMOSD)

• Published in: Acta neurologica Belgica Vol. 125; no. 2; pp. 455 - 462
• Main Authors: Shaik, R. S., Ganaraja, V. H., Bhattacharya, A., Kumar, Manoj, Nitish, L. K., Bhat, M., Pal, P. K., Mahadevan, A., Netravathi, M.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.04.2025
• Subjects: Adult; Aquaporin 4 - immunology; Biomedical and Life Sciences; Biomedicine; Cortical Excitability - physiology; Diffusion Tensor Imaging - methods; Evoked Potentials, Motor - physiology; Female; Humans; Male; Medicine/Public Health; Middle Aged; Neurology; Neuromyelitis Optica - diagnostic imaging; Neuromyelitis Optica - physiopathology; Neuroradiology; Neurosciences; Prospective Studies; Transcranial Magnetic Stimulation - methods; Young Adult; Cortical excitability; NMOSD (Neuromyelitis Optica Spectrum Disorder); MOG (myelin oligodendrocyte glycoprotein); TMS (transcranial magnetic stimulation)
• ISSN: 0300-9009; 2240-2993; 2240-2993
• DOI: 10.1007/s13760-025-02718-x

Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing central nervous system disease most commonly associated with aquaporin-4 antibodies (AQP4-Ab) and Myelin oligodendrocyte glycoprotein (MOG) antibodies. These demyelinating disorders influence cortical excitability, which has be...