Chest imaging classification in Mycoplasma pneumoniae pneumonia is associated with its clinical features and outcomes

• Published in: Respiratory medicine Vol. 221; p. 107480
• Main Authors: Huang, Xia, Gu, Haiyan, Wu, Ruxi, Chen, Lei, Lv, Tian, Jiang, Xinyi, Li, Huili, Guo, Bin, Liu, Jie, Li, Dan, Zhao, Deyu, Liu, Feng
• Format: Journal Article
• Language: English
• Published: England 01.01.2024
• Subjects: Bronchiolitis - complications; Bronchiolitis - diagnostic imaging; Bronchiolitis - epidemiology; Bronchiolitis Obliterans - complications; Bronchopneumonia - complications; Child; Fever; Humans; Mycoplasma pneumoniae; Pneumonia, Mycoplasma - complications; Pneumonia, Mycoplasma - diagnostic imaging; Pneumonia, Mycoplasma - epidemiology; Pulmonary Atelectasis - complications; Retrospective Studies; Chest imaging; Clinical features; Mycoplasma pneumonia; Outcomes; Classification
• ISSN: 0954-6111; 1532-3064; 1532-3064
• DOI: 10.1016/j.rmed.2023.107480

The imaging findings of Mycoplasma pneumoniae pneumonia (MPP) vary; however, few studies have focused on the relationship of imaging classification with clinical manifestations and outcomes. To prospectively investigate whether chest imaging classification in Mycoplasma pneumoniae pneumonia (MPP) is associated with its clinical features and outcomes. A total of 1,401 hospitalized children with MPP were enrolled from January 2019 to December 2021. Imaging findings were categorized as bronchopneumonia and consolidation/atelectasis according to X-ray, and bronchopneumonia, consolidation/atelectasis, bronchiolitis, and mosaic pattern according to computed tomography (CT). Clinical characteristics and outcomes of patients with different imaging classifications were prospectively analyzed based on electronic medical records. Bronchopneumonia was the most common finding (59.6%), while consolidation/atelectasis was the most severe group. Clinical manifestations and laboratory indicators for the consolidation/atelectasis group included serious abnormalities. Further, outcomes of the patients were worse, including having longer total durations of fever and hospitalization, greater hospitalization expenses, and a higher likelihood of developing refractory MPP, necrotizing pneumonia, and bronchiolitis obliterans (BO) in this group. The incidence of bronchiolitis, a disease characterized by a high prevalence of fever, moist rales, and an atopic constitution, tended to increase after the coronavirus disease pandemic and predisposed patients to BO. A mosaic pattern occurred in allergic and young individuals, with wheezing as the main manifestation, with patients having relatively mild symptoms and good outcomes. Different imaging classifications have different clinical features and clinical outcomes; thus, formulating an imaging-based classification system is of great clinical value.