Frontispiece: A Pd-Catalyzed Synthesis of Functionalized Piperidines

Pd Catalysis A readily available cyclic carbamate functions as a general precursor to a range of functionalized piperidine products using a new Pd‐catalyzed annulation strategy. An asymmetric catalytic variant provides a rapid and efficient means to access these heterocycles with high to excellent l...

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Bibliographic Details
Published inChemistry : a European journal Vol. 22; no. 37; pp. np - n/a
Main Authors Allen, Benjamin D. W., Connolly, Matthew J., Harrity, Joseph P. A.
Format Journal Article
LanguageEnglish
Published Weinheim Blackwell Publishing Ltd 05.09.2016
Wiley Subscription Services, Inc
Subjects
annulation
Asymmetry
Catalysis
Chemical reactions
Chemistry
enantioselectivity
Organic chemistry
Pd catalysis
Piperidine
Precursors
Strategy
Synthesis
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Summary:Pd Catalysis A readily available cyclic carbamate functions as a general precursor to a range of functionalized piperidine products using a new Pd‐catalyzed annulation strategy. An asymmetric catalytic variant provides a rapid and efficient means to access these heterocycles with high to excellent levels of enantiocontrol. In addition, these richly functionalized compounds are amenable to further chemoselective elaboration. For more information, see the Communication by J. P. A. Harrity et al. on page 13000 ff.
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ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201683761