Power properties of the likelihood ratio test in an analysis of genetic diseases

A likelihood ratio test concerning a genetic parameter describing in part the nature of a genetic disease is investigated. The test has the undesirable characteristic that its power curve is not a monotonically increasing function of the true value of the parameter being tested.

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Bibliographic Details
Published inBiometrics Vol. 44; no. 4; p. 951
Main Author Shute, N C
Format Journal Article
LanguageEnglish
Published United States 01.12.1988
Subjects
Biometry - methods
Chromosomes, Human, Pair 6
Genetic Diseases, Inborn - genetics
Genetic Linkage
Genetic Markers
Genotype
Haplotypes
HLA Antigens - genetics
Humans
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Summary:A likelihood ratio test concerning a genetic parameter describing in part the nature of a genetic disease is investigated. The test has the undesirable characteristic that its power curve is not a monotonically increasing function of the true value of the parameter being tested.
ISSN:0006-341X
1541-0420
DOI:10.2307/2531726