The effect of host population heterogeneity on epidemic outbreaks

In the first part of this paper, we review old and new results about the influence of host population heterogeneity on (various characteristics of) epidemic outbreaks. In the second part we highlight a modelling issue that so far has received little attention: how do contact patterns, and hence tran...

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Bibliographic Details
Published inMathematics in applied sciences and engineering Vol. 5; no. 1; pp. 1 - 35
Main Authors Bootsma, Martin, Chan, Danny, Diekmann, Odo, Inaba, Hisashi
Format Journal Article
LanguageEnglish
Published Western Libraries 01.03.2024
Subjects
contact structures
epidemic outbreak model
final size
herd immunity threshold
Kermack-McKendrick
static heterogeneity
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Summary:In the first part of this paper, we review old and new results about the influence of host population heterogeneity on (various characteristics of) epidemic outbreaks. In the second part we highlight a modelling issue that so far has received little attention: how do contact patterns, and hence transmission opportunities, depend on the size and the composition of the host population? Without any claim on completeness, we offer a range of potential (quasi-mechanistic) submodels. The overall aim of the paper is to describe the state-of-the-art and to catalyse new work.
ISSN:2563-1926
2563-1926
DOI:10.5206/mase/16718