Piezoelectric Biosensor based on ultrasensitive MEMS system

The lack of ultrasensitive biosensors is the major challenge in the control of pandemics at the very initial stage, so it is necessary to develop new biosensors for the prompt treatment, and the piezoelectric biosensor based on ultrasensitive MEMS system offers a good opportunity. This paper present...

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Bibliographic Details
Published inSensors and actuators. A. Physical. Vol. 376; p. 115664
Main Authors He, Ji-Huan, He, Chun-Hui, Qian, Man-Yu, Alsolami, Abdulrahman Ali
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.10.2024
Subjects
Amplitude-frequency relationship
Covid-19
Electrospinning
Geometrical potential
Medical Equipment
Piezoelectric property
Electrospinning
Covid-19
Piezoelectric property
Amplitude-frequency relationship
Geometrical potential
Medical Equipment
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Summary:The lack of ultrasensitive biosensors is the major challenge in the control of pandemics at the very initial stage, so it is necessary to develop new biosensors for the prompt treatment, and the piezoelectric biosensor based on ultrasensitive MEMS system offers a good opportunity. This paper presents a novel approach using polyvinylidene fluoride (PVDF) unsmooth nanofibers to transfer electronic current. The unique unsmooth surface of these nanofibers provides a high surface energy (geometrical potential), making them highly sensitive to microorganisms (e.g., viruses) absorbed on their surface. The absorption of viruses has an obvious effect on the nanofiber’s displacement and electrical resistivity. This paper presents a mathematical model that demonstrates the system's ultra-sensitivity. This rigorous mathematical analysis shows that even when the pull-in voltage in the PVDF nanofiber changes by just 0.0589 %, a dramatic shift from normal periodic motion to pull-in motion is predicted. This paper provides a new and reliable theoretical way to detect pandemics at the very beginning stage. [Display omitted] •A Polyvinylidene Fluoride(PVDF) nanofiber is used in a micro-electromechanical system.•PVDF nanofiber has good piezoelectric property.•A mathematical model is established to show the extremely sensitiveness of the MEMS-based biosensor.
ISSN:0924-4247
1873-3069
DOI:10.1016/j.sna.2024.115664