The novel synthesis of 5-cyano-1-azabicyclo[3.3.0]octane
5-Cyano-1-azabicyclo[3.3.0]octane (1), which is a key intermediary material to some medicines, was prepared from 1,7-dichloroheptan-4-one (7) via only one step under mild conditions. The reaction mechanism is also discussed.
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Published in | Heterocycles Vol. 45; no. 8; pp. 1447 - 1450 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
OXFORD
Elsevier
1997
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Subjects | |
Online Access | Get more information |
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Summary: | 5-Cyano-1-azabicyclo[3.3.0]octane (1), which is a key intermediary material to some medicines, was prepared from 1,7-dichloroheptan-4-one (7) via only one step under mild conditions. The reaction mechanism is also discussed. |
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ISSN: | 0385-5414 |
DOI: | 10.3987/com-97-7845 |