Phytochemical and chemotaxonomic study on the whole plants of Ligularia sagitta

• Published in: Biochemical systematics and ecology Vol. 80; pp. 122 - 127
• Main Authors: Gong, Yuan, Meng, Xian-Hua, Zhu, Ying
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.10.2018
• Subjects: Asteraceae; Chemical constituents; Chemotaxonomy; Ligularia sagitta; Chemotaxonomy; Chemical constituents; Ligularia sagitta; Asteraceae
• ISSN: 0305-1978; 1873-2925
• DOI: 10.1016/j.bse.2018.07.006

The phytochemical study of the whole plants of Ligularia sagitta led to the isolation of 26 compounds, including a new eremophilane-type sesquiterpene (1) and twenty-five known compounds, i.e. eleven sesquiterpenes (2–12), one diterpene (13), one triterpene (14), one sterol (15), four flavonoids (16–19), one lignan (20), one cumarin (21), three phenylpropanoids (22–24), one benzene derivative (25), and one alkaloid (26). The structures of all isolated compounds were elucidated on the basis of extensive spectroscopic methods (HRESIMS, 1D and 2D NMR experiments), as well as by comparison with literature data. Among them, ten compounds (4–6, 8–9, 13, 16–17, 19, 26) were reported for the first time from the genus Ligularia. The chemotaxonomic significance of the isolated compounds is discussed. •26 compounds were isolated from Ligularia sagitta.•The structure of a new eremophilane-type sesquiterpene were elucidated by spectroscopic methods.•Ten compounds were first reported from the genus Ligularia.•Chemotaxonomic relationship between L. sagitta and the genus Ligularia was discussed.•Sesquiterpenoids and phenolics could be considered as chemotaxonomic markers for the genus Ligularia.