One‐Pot Pseudo Five‐Component Synthesis of Some New bis(Quinazolinon‐4(1H)‐one) Derivatives

A versatile pathway for the synthesis of novel bis(quinazolinon‐4(1H)‐one) derivatives by one‐pot pseudo five‐component condensation of two molecules isatoic anhydrides, two molecules orthoesters, and diamines in high yields and short reaction time is described. The work‐up is easy, and the products...

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 54; no. 1; pp. 484 - 488
Main Authors Mohammadi, Ali A., Taheri, Salman, Askari, Saber
Format Journal Article
LanguageEnglish
Published HOBOKEN Wiley 01.01.2017
Wiley Subscription Services, Inc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
2,3-DIHYDROQUINAZOLIN-4(1H)-ONES
REUSABLE CATALYST
MULTICOMPONENT REACTIONS
3-COMPONENT SYNTHESIS
SOLVENT-FREE CONDITIONS
QUINAZOLINE
IONIC LIQUID
MICROWAVE IRRADIATION
EFFICIENT
KAL(SO4)CENTER-DOT-12HO
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Summary:A versatile pathway for the synthesis of novel bis(quinazolinon‐4(1H)‐one) derivatives by one‐pot pseudo five‐component condensation of two molecules isatoic anhydrides, two molecules orthoesters, and diamines in high yields and short reaction time is described. The work‐up is easy, and the products are obtained in good‐to‐excellent yields and high purity.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.2609