An Efficient One‐Pot Four‐Component Synthesis of Some New Spirooxindole Dihydropyridine Using Alum as a Heterogeneous Green Catalyst

4‐Nitro‐2,3‐dihydrospiro[imidazo[1,2‐a]indeno[2,1‐e]pyridine‐5,3′‐indoline]‐2′,6(1H)‐dione derivatives have been synthesized in good yields in a one‐pot four‐component, and efficient process by reaction of corresponding isatins, 1,3‐indandione, diamine, and nitro ketene dithioacetal in the presence...

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 54; no. 3; pp. 2085 - 2089
Main Authors Mohammadi, Ali A., Taheri, Salman, Amouzegar, Ali
Format Journal Article
LanguageEnglish
Published HOBOKEN Wiley 01.05.2017
Wiley Subscription Services, Inc
Subjects
Alum
Catalysts
Chemistry
Chemistry, Organic
Diamines
Isatin
Multicomponent reactions
Physical Sciences
Science & Technology
spiro oxindole
DESIGN
ANTIBACTERIAL
OXINDOLES
spiro oxindole
KAL(SO4)CENTER-DOT-12HO
REUSABLE CATALYST
Multicomponent reactions
Isatin
BIOLOGICAL EVALUATION
AGENTS
INHIBITORS
Alum
DERIVATIVES
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Summary:4‐Nitro‐2,3‐dihydrospiro[imidazo[1,2‐a]indeno[2,1‐e]pyridine‐5,3′‐indoline]‐2′,6(1H)‐dione derivatives have been synthesized in good yields in a one‐pot four‐component, and efficient process by reaction of corresponding isatins, 1,3‐indandione, diamine, and nitro ketene dithioacetal in the presence of KAl(SO4)2.12H2O (Alum) as a nontoxic and easily available heterogeneous green catalyst.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.2757