Asymmetric epoxidation of cinnamyl alcohol catalyzed by silica-supported casein-Co complex

• Published in: Polymers for advanced technologies Vol. 13; no. 3-4; pp. 216 - 219
• Main Authors: Zhang, Xi, Han, Bing, Hua, Yu-Ning, Huang, Mei-Yu, Jiang, Ying-Yan
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.03.2002
• Subjects: (2R,3R)‐(+)‐3‐phenylglycidol; 2R; 3R)-(+)-3-phenylglycidol; asymmetric epoxidation; casein-Co complex; chiral catalyst; natural biopolymer
• ISSN: 1042-7147; 1099-1581
• DOI: 10.1002/pat.176

Silica‐supported casein–Co complex (Si‐CA–Co) was prepared from silica, casein and cobalt chloride, and found to be useful as a chiral catalyst for the asymmetric epoxidation of cinnamyl alcohol to (2R,3R)‐(+)‐3‐phenylglycidol at 70 °C and under 1 atmospheric oxygen pressure. When a proper content of cobalt in the Si‐CA–Co complex and suitable reaction conditions were selected, the product and optical yield could be amounted to 70.6 and 92.0%, respectively, and the Si‐CA–Co complex could be reused several times without any remarkable change in the optical catalytic activity. Copyright © 2002 John Wiley & Sons, Ltd.