The amount of skeletal muscle mass is associated with arterial stiffness in hemodialysis patients

• Published in: Therapeutic apheresis and dialysis Vol. 27; no. 1; pp. 24 - 30
• Main Authors: Ulgen, Cansu, Ozturk, Ilyas, Sahin, Murat, Guzel, Fatma Betul, Oguz, Ayten, Altunoren, Orcun, Gungor, Ozkan
• Format: Journal Article
• Language: English
• Published: Kyoto, Japan John Wiley & Sons Australia, Ltd 01.02.2023
• Subjects: arterial stiffness; Blood Pressure - physiology; hemodialysis; Humans; Muscle, Skeletal; Renal Dialysis; sarcopenia; Sarcopenia - etiology; Vascular Stiffness - physiology; arterial stiffness; hemodialysis; sarcopenia
• ISSN: 1744-9979; 1744-9987
• DOI: 10.1111/1744-9987.13853

Introduction Sarcopenia was determined to be associated with increased arterial stiffness in the nondialysis patient population, but there is no available data on this subject in dialysis patients. Methods A total of 79 patients were included in the study. Sarcopenia was diagnosed according to the EWSGOP‐2 criteria. Arterial stiffness was measured noninvasively with a mobile‐O‐Graph device. Results Skeletal muscle mass was observed to be positively correlated with weight, body mass index, creatinine, and uric acid, while negatively correlated with augmentation index. There was a correlation between augmentation index and sodium, phosphorus, systolic blood pressure, diastolic blood pressure, cardiac index, muscle percentage, fat percentage, and skeletal muscle mass. When the determinants of augmentation index in the linear regression analysis were viewed, just the systolic blood pressure and skeletal muscle mass were observed to be the determinant. Conclusion Decreased skeletal muscle mass contributes to increased arterial stiffness in hemodialysis patients.