Two-day trimethoprim-sulfamethoxazole treatment of pharyngeal gonorrhea
The efficacy of three different regimens of oral medication for pharyngeal gonorrhea was examined in a study of 119 patients. Of 34 patients treated with 1.4 g of pivampicillin plus 1.0 g of probenecid, both taken once a day for five days, 33 (97.1%) were cured. The other two regimens consisted of t...
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Published in | Sexually transmitted diseases Vol. 15; no. 2; p. 116 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
United States
01.04.1988
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Subjects | |
Online Access | Get more information |
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Summary: | The efficacy of three different regimens of oral medication for pharyngeal gonorrhea was examined in a study of 119 patients. Of 34 patients treated with 1.4 g of pivampicillin plus 1.0 g of probenecid, both taken once a day for five days, 33 (97.1%) were cured. The other two regimens consisted of tablets containing sulfamethoxazole (400 mg) and trimethoprim (80 mg). Of 36 patients treated with a single ten-tablet dose on the first day, two five-tablet doses on the second day, and two three-tablet doses for the next three to five days, 35 (97.2%) were cured. Of 49 patients treated with a single ten-tablet dose on the first day and two five-tablet doses on the second day, 44 (89.8%) were cured. The cure rates for the three regimens were not significantly different (P greater than 0.05). Therefore, we conclude that a two-day trimethoprim-sulfamethoxazole regimen is quick, inexpensive, and reliable in the treatment of pharyngeal gonorrhea. |
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ISSN: | 0148-5717 |
DOI: | 10.1097/00007435-198804000-00011 |