Multicomponent reactions for the synthesis of heterocycles

Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one-pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of start...

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Bibliographic Details
Published inChemistry, an Asian journal Vol. 5; no. 11; p. 2318
Main Authors Jiang, Bo, Rajale, Trideep, Wever, Walter, Tu, Shu-Jiang, Li, Guigen
Format Journal Article
LanguageEnglish
Published Germany 02.11.2010
Subjects
Heterocyclic Compounds - chemical synthesis
Heterocyclic Compounds - chemistry
Molecular Structure
Organic Chemistry Phenomena
Stereoisomerism
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Summary:Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one-pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and manpower. Moreover, the reaction period can be substantially shortened. This Review covers recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives.
ISSN:1861-471X
DOI:10.1002/asia.201000310