Latent prostatic carcinoma: pathological and epidemiological aspects

In conclusion, a review of the epidemiology and pathology of latent prostatic cancer suggests this tumor to be the probable initial phase of a biological continuum that ends with metastatic cancer. Histological grade and tumor volume are highly correlated, as are histological grade and mitotic index...

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Bibliographic Details
Published inJapanese journal of clinical oncology Vol. 19; no. 4; p. 319
Main Authors Yatani, R, Kusano, I, Shiraishi, T, Hayashi, T, Stemmermann, G N
Format Journal Article
LanguageEnglish
Published England 01.12.1989
Subjects
Aged
Humans
Hyperplasia
Incidence
Male
Middle Aged
Neoplasm Staging
Precancerous Conditions - epidemiology
Precancerous Conditions - pathology
Prostatic Neoplasms - epidemiology
Prostatic Neoplasms - pathology
Risk Factors
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Summary:In conclusion, a review of the epidemiology and pathology of latent prostatic cancer suggests this tumor to be the probable initial phase of a biological continuum that ends with metastatic cancer. Histological grade and tumor volume are highly correlated, as are histological grade and mitotic index. It has also been suggested that atypical intraductal hyperplasia is, in turn, a precursor of carcinoma. This concept gains support from the close association of the two conditions among younger (less than 60 years of age) patients and from their similar mitotic and labeling indices.
ISSN:0368-2811
DOI:10.1093/oxfordjournals.jjco.a039321