D-Amino acid production from racemic amino acids by a microbial asymmetric degradation

To obtain D-amino acid from a mixture of racemic amino acids, Proteus vulgaris, having the ability of selective degradation of L-isomer in various DL-amino acids mixtures, was used as a biocatalyst. D-Isomer crystals of valine, leucine, isoleucine, histidine and ornithine were isolated at a good yie...

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Bibliographic Details
Published inBiotechnology techniques Vol. 11; no. 12; pp. 913 - 916
Main Authors TAKAHASHI, E, FURUI, M, SHIBATANI, T
Format Journal Article
LanguageEnglish
Published London Chapman and Hall 01.12.1997
Subjects
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Biodegradation
Stereoselectivity
D stereoisomer
Aminoacid
Production
Racemate
Bacteria
Proteus vulgaris
Enterobacteriaceae
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Summary:To obtain D-amino acid from a mixture of racemic amino acids, Proteus vulgaris, having the ability of selective degradation of L-isomer in various DL-amino acids mixtures, was used as a biocatalyst. D-Isomer crystals of valine, leucine, isoleucine, histidine and ornithine were isolated at a good yield (25 similar to 41%) from the reaction mixture after 24 similar to 72 hours.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0951-208X
1573-6784
DOI:10.1023/A:1018470502118