Modulation of the enzyme-like activity of CuAsp nanozyme by gallic acid and the selective detection of bisphenol A in infant food packaging

• Published in: Analytical methods Vol. 16; no. 5; pp. 751 - 758
• Main Authors: Wang, Luwei, Li, Jie, Lei, Lulu, Li, Yongxin, Huang, Hui
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.02.2024
• Subjects: Antioxidants; Aspartic acid; Benzhydryl Compounds; Bisphenol A; Catalytic activity; Colorimetry; Copper; Drinking water; Enzymatic activity; Food Packaging; Gallic Acid; Humans; Infants; Interference; Laccase; Modulation; Peroxidase; Phenols; Water analysis; Water sampling
• ISSN: 1759-9660; 1759-9679; 1759-9679
• DOI: 10.1039/d3ay01930f

The activity modulation of nanozymes with multi-enzymatic activities has both opportunities and challenges in practical applications. In this study, we found firstly that gallic acid erosion had a significant inhibitory effect on the peroxidase-catalyzed colorimetric reaction process of copper aspartate nanozyme prepared based on aspartic acid and copper (CuAsp), and the laccase-like catalytic activity remained almost unchanged. A sensing strategy for bisphenol A was then developed based on the laccase-like activity of GA-CuAsp synthesized by gallic acid (GA) acid erosion of CuAsp, which may have less interference due to the peroxidase-like activity. The developed sensing strategy had good selectivity and interference resistant ability, with a detection limit of 0.75 μmol L −1 . In addition, the method was successfully applied to detecting BPA in plastic bottled drinking water samples and infant food packaging. Modulation of the enzyme-like activity of CuAsp nanozyme by gallic acid and the selective detection of bisphenol A in infant food packaging and plastic bottles of drinking water.