Efficacy of anthelmintics against parasitic infections and their treatment effect on the production and blood indices in Black Bengal goats in Bangladesh

• Published in: Turkish Journal of Veterinary and Animal Sciences; Year: 2012 Volume: 36 Issue: 4; 400-408
• Main Authors: HASSAN, Mohammad Mahmudul, HOQUE, Md. Ahasanul, ISLAM, S. K. M. Azizul, KHAN, Sahaneaz Ali, HOSSAIN, Mohammad Belayet, BANU, Qamar
• Format: Journal Article
• Language: English
• Published: TUBITAK 01.01.2012
• Subjects: Key words: Black Bengal goat, anthelmintics, efficacy, hematological and biochemical parameters, body weight
• ISSN: 1303-6181; 1300-0128
• DOI: 10.3906/vet-1010-492

The Black Bengal goat is an important livestock animal in Bangladesh. To assess the efficacy of selective anthelmintics against ecto- and endoparasites of Black Bengal goats and their treatment effects on body-weight gains and hematobiochemical indices, a field trial was conducted at Pahartali Thana in Chittagong district. The study was performed during the period of February 2006 to January 2007. Goats were treated with CEVAMEC®-1% (ivermectin) (T1), ENDEX®-1500 (triclabendazole along with levamisole) (T2), and a placebo (T3, untreated). A reduction of eggs per gram count was very significant from day 7 (91.3% reduction) through day 28 (100%) with the treatment of ivermectin. The reduction rate of eggs per gram was also significant with the treatment of triclabendazole along with levamisole (75.8%-94.7%). Both of the drugs were equally significant against endoparasitic infections of goats in this study (P < 0.05; t-test). The percentage efficacy of ivermectin was also recorded against ticks and lice of goats from day 7 through day 28 of the trial period. The packed cell volume and hemoglobin levels increased significantly (P < 0.05) in both of the treated groups (T1 and T2), which was indicative of effective treatments of those trial drugs. The total serum protein and calcium levels also increased significantly (P < 0.05) in both of the treated groups (T1 and T2) as compared to the untreated group (T3), which was also suggestive of effective treatment. The level of serum glutamate pyruvate transaminase (SGPT) and serum glutamate oxaloacetate transaminase (SGOT) declined significantly (P < 0.05) in both of the treated groups (T1 and T2). This result also indicates the success of those drug actions against endoparasites of goats. In conclusion, either of the drug regimens can be used against parasitic infections of backyard goats. However, in order to design a proper anthelmintic schedule against parasitic infections in backyard goats, a long-term trial, covering seasons of a calendar year, needs to be conducted.