Sulfasalazine-Loaded Copper-Tannic Acid Coordination Nanozyme Enables ROS Scavenging and Immunomodulation for Inflammatory Bowel Disease Therapy

• Published in: Advanced healthcare materials p. e2403738
• Main Authors: Yan, Jian-Hua, Liang, Chun-Xiao, Ma, Ran-Ran, Li, Bo-Jia, Chen, Qi-Wen, Li, Wen, Zeng, Xuan, Zhang, Xian-Zheng
• Format: Journal Article
• Language: English
• Published: Germany 08.12.2024
• Subjects: immunomodulation; sulfasalazine; nanozyme; inflammatory bowel disease; ROS

Inflammatory bowel disease (IBD) is associated with elevated levels of reactive oxygen species (ROS) and an increased expression of proinflammatory cytokines. Anti-inflammatory drugs, monoclonal antibodies, and immunomodulators are commonly employed to control the inflammatory response in the manage...