Lending a hand to asymmetric trifluoromethylthiolation： enantioselective [2,3]-sigmatropic rearrangement of sulfonium ylides

The introduction of a trifluoromethanesulfenyl group （SCF3） into organic molecules can, in principle, significantly en- hance the cell-membrane permeability, metabolic stability and bioavailability because of its high lipophilicity and intrinsic electron-withdrawing properties. As a consequence,

Saved in:
Bibliographic Details
Published inScience China. Chemistry Vol. 60; no. 12; pp. 1565 - 1566
Main Authors Mao, Guoliang, Chen, Lei, Wang, Congyang
Format Journal Article
LanguageEnglish
Published Beijing Science China Press 01.12.2017
Springer Nature B.V
Subjects
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Enantiomers
Highlights
Online AccessGet full text

Cover

More Information
Summary:The introduction of a trifluoromethanesulfenyl group （SCF3） into organic molecules can, in principle, significantly en- hance the cell-membrane permeability, metabolic stability and bioavailability because of its high lipophilicity and intrinsic electron-withdrawing properties. As a consequence,
Bibliography:The introduction of a trifluoromethanesulfenyl group （SCF3） into organic molecules can, in principle, significantly en- hance the cell-membrane permeability, metabolic stability and bioavailability because of its high lipophilicity and intrinsic electron-withdrawing properties. As a consequence
Lending a hand ; asymmetric trifluoromethyl;thiolation
11-5839/O6
ISSN:1674-7291
1869-1870
DOI:10.1007/s11426-017-9113-5