Crystal structure, physicochemical properties, Hirshfeld surface analysis and antibacterial activity assays of transition metal complexes of 6-methoxyquinoline

• Published in: New journal of chemistry Vol. 42; no. 9; pp. 7166 - 7176
• Main Authors: Villa-Pérez, C., Ortega, I. C., Vélez-Macías, A., Payán, A. M., Echeverría, G. A., Soria, D. B., Valencia-Uribe, G. C.
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 2018
• Subjects: Cobalt; Coordination compounds; Copper; Crystal lattices; Crystal structure; Fluorescence; Fourier transforms; Hydrothermal crystal growth; Ligands; Nickel; Oxygen production; Silver; Singlet oxygen; Surface analysis (chemical)
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/C8NJ00661J

Five monomeric complexes of Co( ii ), Cu( ii ), Ni( ii ), Zn( ii ) and Ag( i ) with 6-methoxyquinoline (6-MeOQ) as ligand have been prepared, and their crystal structures have been determined by single X-ray diffractions. The Cu( ii ), Ni( ii ) and Zn( ii ) complexes are formulated as M(6-MeOQ) 2 Cl 2 , completing MN 2 Cl 2 coordination spheres. On the other hand, Co( ii ) and Ag( i ) compounds are ionic with formulae [Ag(6-MeOQ) 2 ] + NO 3 − and H(6-MeOQ) + [Co(6-MeOQ)Cl 3 ] − (where H(6-MeOQ) + is the protonated ligand). Hirshfeld surface analysis was employed to study the intermolecular interactions in the crystal lattices and from these studies it was found that π-stacking contacts play an important role. Besides, the complexes have been characterized by FTIR, UV-visible and emission spectroscopies. The singlet oxygen production and fluorescence quantum yields were measured for all the complexes employing steady-state methodologies. Finally, the antibacterial activity of the complexes was screened against both Gram-positive and Gram-negative bacteria.