Fasting hyperglycemia in type I diabetes mellitus

The differential diagnosis of fasting hyperglycemia in type I diabetes includes the Somogyi effect, the dawn phenomenon, and insufficient insulin administration. To determine the causes of fasting hyperglycemia and their effect on subsequent daytime blood glucose control, the authors retrospectively...

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Published inJournal of Osteopathic Medicine (Online) Vol. 93; no. 7; p. 769
Main Authors Mozersky, Robert P., Bahl, Vijay K., Patel, Hitendra, Palushock, Sharon, Yamakawa, Harusigh, Mook, William, Patel, Nilesh, Basuray, Rita, Velez-Giraldo, Juan R.
Format Journal Article
LanguageEnglish
Published United States American Osteopathic Association 01.07.1993
Subjects
Adult
Blood Glucose - analysis
Circadian Rhythm
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - drug therapy
Fasting
Female
Growth Hormone - blood
Humans
Hydrocortisone - blood
Hyperglycemia - blood
Hyperglycemia - etiology
Hyperglycemia - physiopathology
Insulin - adverse effects
Insulin - therapeutic use
Male
Middle Aged
Retrospective Studies
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Summary:The differential diagnosis of fasting hyperglycemia in type I diabetes includes the Somogyi effect, the dawn phenomenon, and insufficient insulin administration. To determine the causes of fasting hyperglycemia and their effect on subsequent daytime blood glucose control, the authors retrospectively reviewed blood glucose profiles of 126 patients with type I diabetes. The Somogyi effect accounted for 12.6% of all instances of fasting hyperglycemia, the dawn phenomenon, 24.1%, and poor control, 63.3%. Measurement of 3 AM and 5 AM blood glucose values is the key to making a correct diagnosis. Once a patient's fasting hyperglycemia is placed in one of these groups, appropriate treatment can be started.
ISSN:0098-6151
2702-3648
2702-3648
DOI:10.7556/jaoa.1993.93.7.769