Risperidone N‐oxide hydrogen peroxide methanol solvate

• Published in: Acta crystallographica. Section E, Structure reports online Vol. 61; no. 8; pp. o2515 - o2517
• Main Authors: Ravikumar, K., Sridhar, B., Manjunatha, S. G., Thomas, Saji
• Format: Journal Article
• Language: English
• Published: 5 Abbey Square, Chester, Cheshire CH1 2HU, England Munksgaard International Publishers 01.08.2005
• ISSN: 1600-5368; 1600-5368
• DOI: 10.1107/S1600536805022002

In the crystal structure of the title compound {systematic name: 4‐(6‐fluoro‐1,2‐benzisoxazol‐3‐yl)‐1‐hydr­oxy‐1‐[2‐(2‐meth­yl‐4‐oxo‐3,4,6,7,8,9‐hexa­hydro‐2H‐pyrido[1,2‐a]pyrimid­in‐3‐yl)eth­yl]piperidine N‐oxide hydrogen peroxide methanol solvate}, C23H27FN4O3·H2O2·CH3OH, the asymmetric unit contains one mol­ecule of risperidone N‐oxide, one methanol solvent mol­ecule and one hydrogen peroxide mol­ecule. The piperidine ring adopts a chair conformation, while the tetra­hydro­pyridine ring has a sofa conformation. The hydrogen peroxide mol­ecule links the risperidone mol­ecules to form a chain. O—H⋯O and C—H⋯O inter­actions stabilize the crystal packing.