Osteomyelitis, Venous Thrombosis, and Septic Emboli in a Pediatric Patient: A Case Report

New virulence factors, such as the Panton-Valentine leukocidin (PVL), are appearing during Staphylococcus aureus infections occurring in the pediatric population. Such factors increase the aggressiveness and risk of dissemination of the bacteria, causing infections to be life-threatening. An early d...

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Published inPlastic surgical nursing Vol. 40; no. 4; p. 197
Main Authors Jordà Gómez, Pablo, Vanaclocha, Nieves, Ferràs Tarrago, Joan, Bretón Martínez, Jose Rafael, Blasco Mollá, Maria Ángeles
Format Journal Article
LanguageEnglish
Published United States 01.10.2020
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Summary:New virulence factors, such as the Panton-Valentine leukocidin (PVL), are appearing during Staphylococcus aureus infections occurring in the pediatric population. Such factors increase the aggressiveness and risk of dissemination of the bacteria, causing infections to be life-threatening. An early diagnosis is thus especially important. We present a case of osteomyelitis, venous thrombosis, and septic emboli occurring in a pediatric patient that should trigger suspicion of a PVL-positive strain. A multidisciplinary approach is necessary to enable rapid diagnosis and early treatment, which is essential for successful management of these infections. Management is based on broad-spectrum antibiotics, in combination with aggressive surgical treatment and antithrombotic therapy. In patients infected with S. aureus whose condition worsens quickly, PVL gene sequencing should be considered.
ISSN:1550-1841
DOI:10.1097/PSN.0000000000000332