Low-Dose Abdominal CT for Evaluating Suspected Appendicitis in Adolescents and Young Adults: Review of Evidence

• Published in: Korean Journal of Radiology Vol. 23; no. 5; pp. 517 - 528
• Main Authors: Park, Ji Hoon, Salminen, Paulina, Tannaphai, Penampai, Lee, Kyoung Ho
• Format: Journal Article Book Review
• Language: English
• Published: Korea (South) The Korean Society of Radiology 01.05.2022; 대한영상의학회
• Subjects: Abdomen; Acute Disease; Adolescent; Appendectomy; Appendicitis; Appendicitis - diagnostic imaging; Cancer; Carcinogens; Child; Cohort analysis; Drug dosages; Gastrointestinal Imaging; Humans; Magnetic resonance imaging; Radiation; Radiation Dosage; Sensitivity and Specificity; Teenagers; Tomography, X-Ray Computed; Ultrasonic imaging; Young Adult; Young adults; 방사선과학; United States > US; South Korea; Appendicitis; Radiation dosage; Evidence-based practice; Multidetector computed tomography
• ISSN: 1229-6929; 2005-8330
• DOI: 10.3348/kjr.2021.0596

Due to its excellent diagnostic performance, CT is the mainstay of diagnostic test in adults with suspected acute appendicitis in many countries. Although debatable, extensive epidemiological studies have suggested that CT radiation is carcinogenic, at least in children and adolescents. Setting aside the debate over the carcinogenic risk of CT radiation, the value of judicious use of CT radiation cannot be overstated for the diagnosis of appendicitis, considering that appendicitis is a very common disease, and that the vast majority of patients with suspected acute appendicitis are adolescents and young adults with average life expectancies. Given the accumulated evidence justifying the use of low-dose CT (LDCT) of only 2 mSv, there is no reasonable basis to insist on using radiation dose of multi-purpose abdominal CT for the diagnosis of appendicitis, particularly in adolescents and young adults. Published data strongly suggest that LDCT is comparable to conventional dose CT in terms of clinical outcomes and diagnostic performance. In this narrative review, we will discuss such evidence for reducing CT radiation in adolescents and young adults with suspected appendicitis.