Epidemiology of acute decompensated heart failure in India : The AFAR study (Acute failure registry study)

• Published in: Journal of the Practice of Cardiovascular Sciences Vol. 1; no. 1; pp. 35 - 38
• Main Authors: Seth, Sandeep, Khanal, Suraj, Ramakrishnan, Sivasubramanian, Gupta, Namit, Bahl, Vinay
• Format: Journal Article
• Language: English
• Published: Medknow Publications and Media Pvt. Ltd 01.01.2015; Wolters Kluwer Medknow Publications
• Subjects: Acute; Care and treatment; decompensated; Development and progression; Heart failure; Hospital services; India; Statistics; India
• ISSN: 2395-5414; 2454-2830
• DOI: 10.4103/2395-5414.157563

Objectives: There is a paucity of data on acute decompensated heart failure (ADHF) in Indian patients. We herein report the in-hospital and 6-month outcome of Indian patients admitted with ADHF. Methods: We prospectively enrolled consecutive patients with ADHF due to systolic dysfunction in the acute failure registry and followed them up for at least 6 months. We analyzed the data on death and hospitalization of the first 90 patients on death and hospitalization over 6-months. Results: A total of 90 patients were enrolled with a mean age of 53.5 ± 17. 7 years and the majority were male (63%). The mean left ventricular ejection fraction was 29.2± 11.9%. The in hospital mortality was 30.8%. Postdischarge 6-month major adverse event (re-hospitalization/mortality combined) and mortality rates were 39.5% and 26.3%, respectively. Conclusions: These data from a single referral center provide insights into the current status of acute HF care in India. We report a higher in-hospital and follow-up mortality rates in ADHF patients who present at younger ages than reported in Western literature.