Correction: ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer

• Published in: Journal of experimental & clinical cancer research Vol. 44; no. 1; pp. 23 - 4
• Main Authors: Su, Pingping, Mao, Xiaodan, Ma, Jincheng, Huang, Lixiang, Yu, Lirui, Tang, Shuting, Zhuang, Mingzhi, Lu, Zhonglei, Osafo, Kelvin Stefan, Ren, Yuan, Wang, Xinrui, Lin, Xite, Huang, Leyi, Huang, Xiaoli, Braicu, Elena Ioana, Sehouli, Jalid, Sun, Pengming
• Format: Journal Article
• Language: English
• Published: England BioMed Central 25.01.2025; BMC
• ISSN: 1756-9966; 0392-9078; 1756-9966
• DOI: 10.1186/s13046-025-03292-z

E Representative TEM images of KLE and HEC-1A cells in diferent ERRα expression groups treated with 7 µg DDP for 12 h. The mitochondrial membrane structure was indistinctly dissolved, the matrix was dissolved in a large area, and the crest was broken in siERRα cells, as indicated with the red arrows; the yellow arrows indicate ERRα-overexpressing EC cells whose mitochondrial membrane structure was relatively clear, the matrix was partially dissolved, and the cristae were slightly broken. Abbreviations: EC, endometrial cancer; IC50, inhibitory concentration; PI, propidium iodide; TEM, transmission electron microscopy; 2-DG, 2-deoxy-glucose Full size image Correct Fig. 3 Fig. 3 figure 2 Overexpression of estrogen-related receptor alpha (ERRα) enhances pyroptosis resistance accompanied by glycolytic metabolism, leading to cisplatin (DDP) resistance of EC cells. E Representative TEM images of KLE and HEC-1A cells in diferent ERRα expression groups treated with 7 µg DDP for 12 h. The mitochondrial membrane structure was indistinctly dissolved, the matrix was dissolved in a large area, and the crest was broken in siERRα cells, as indicated with the red arrows; the yellow arrows indicate ERRα-overexpressing EC cells whose mitochondrial membrane structure was relatively clear, the matrix was partially dissolved, and the cristae were slightly broken. Abbreviations: EC, endometrial cancer; IC50, inhibitory concentration; PI, propidium iodide; TEM, transmission electron microscopy; 2-DG, 2-deoxy-glucose Full size image The correction does not compromise the validity of the conclusions and the overall content of the article.