Tandem cyclization of phytosphingosine

Phytosphingosine is easily cyclized during the protection of amino group with phthalic acid derivatives to form trisubstituted tetrahydrofuran structure (2) by the attack of 4-hydroxyl group to the terminal carbon. The structure of compound (2) was confirmed by X-Ray crystallography and synthetic me...

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Bibliographic Details
Published inHeterocycles Vol. 55; no. 6; pp. 1127 - 1132
Main Authors Jo, SY, Kim, HC, Jeon, DJ, Kim, HR
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.06.2001
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
SPHINGOSINE
GLYCOSPHINGOLIPIDS
CERAMIDES
CYCLE
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Summary:Phytosphingosine is easily cyclized during the protection of amino group with phthalic acid derivatives to form trisubstituted tetrahydrofuran structure (2) by the attack of 4-hydroxyl group to the terminal carbon. The structure of compound (2) was confirmed by X-Ray crystallography and synthetic method.
ISSN:0385-5414
DOI:10.3987/com-01-9187