Correlation between sweat glucose and blood glucose in subjects with diabetes

Sweat contains glucose that can accurately reflect blood glucose. However, skin surface glucose can confound these measurements. A perfusion method was used to rapidly harvest sweat from forearm sites on human subjects. The sweat samples were analyzed for glucose by high-performance liquid chromatog...

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Bibliographic Details
Published inDiabetes technology & therapeutics Vol. 14; no. 5; p. 398
Main Authors Moyer, James, Wilson, Donald, Finkelshtein, Irina, Wong, Bruce, Potts, Russell
Format Journal Article
LanguageEnglish
Published United States 01.05.2012
Subjects
Adult
Blood Glucose - metabolism
Chromatography, High Pressure Liquid
Diabetes Mellitus, Type 1 - metabolism
Diabetes Mellitus, Type 2 - metabolism
Female
Forearm
Glucose - metabolism
Humans
Male
Reproducibility of Results
Sensitivity and Specificity
Sweat - metabolism
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Summary:Sweat contains glucose that can accurately reflect blood glucose. However, skin surface glucose can confound these measurements. A perfusion method was used to rapidly harvest sweat from forearm sites on human subjects. The sweat samples were analyzed for glucose by high-performance liquid chromatography methods and compared with the results obtained with a blood glucose meter. The results of 23 different studies of seven individual subjects with diabetes show a strong correlation between sweat glucose and blood glucose. Sweat glucose, when properly harvested to prevent contamination from other sources on the skin's surface, can accurately reflect blood glucose levels.
ISSN:1557-8593
DOI:10.1089/dia.2011.0262