Citrate in the management of urolithiasis

Citrate therapy for recurrent calcium urolithiasis has become common over the last decade. The hypotheses that chronic stone formers must have biochemical defects that increase recurrence risks have instigated medical therapy directed at these defects. The utilization of stone clinics, detailed meta...

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Bibliographic Details
Published inJournal of endourology Vol. 13; no. 9; p. 687
Main Authors Pattaras, J G, Moore, R G
Format Journal Article
LanguageEnglish
Published United States 01.11.1999
Subjects
Administration, Oral
Citrates - therapeutic use
Citrates - urine
Humans
Urinary Calculi - drug therapy
Urinary Calculi - prevention & control
Urinary Calculi - surgery
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Summary:Citrate therapy for recurrent calcium urolithiasis has become common over the last decade. The hypotheses that chronic stone formers must have biochemical defects that increase recurrence risks have instigated medical therapy directed at these defects. The utilization of stone clinics, detailed metabolic evaluations, and meticulous follow-up of recurrent stone formers has led to a greater understanding and knowledge of treatment options. Citrate therapy has been used like aspirin in the medical community perhaps without a clear understanding of its mechanism of action and indications. This article provides a synopsis of citrate use in the medical and surgical treatment of urolithiasis.
ISSN:0892-7790
DOI:10.1089/end.1999.13.687