A Case of Diffuse Endocapillary Proliferative Glomerulonephritis Associated with Polymyalgia Rheumatica

A 70-year-old man complained of muscle pain in his neck, shoulders and pelvic girdle. Proteinuria and hematuria subsequently developed. Blood analysis showed increased acute phase reactants. The histology of renal biopsy showed diffuse endocapillary proliferative glomerulonephritis. There were no si...

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Published inCase reports in nephrology and dialysis Vol. 2; no. 2; pp. 158 - 164
Main Authors Takeshima, Eri, Morishita, Yoshiyuki, Ogura, Manabu, Ito, Chiharu, Saito, Osamu, Takemoto, Fumi, Ando, Yasuhiro, Muto, Shigeaki, Yumura, Wako, Kusano, Eiji
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 15.11.2012
Subjects
Published: November 2012
Endocapillary proliferative glomerulonephritis
Polymyalgia rheumatica
Nephrotic syndrome
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Summary:A 70-year-old man complained of muscle pain in his neck, shoulders and pelvic girdle. Proteinuria and hematuria subsequently developed. Blood analysis showed increased acute phase reactants. The histology of renal biopsy showed diffuse endocapillary proliferative glomerulonephritis. There were no signs of autoimmune diseases, malignancies and bacterial or viral infections. His extrarenal symptoms and the results of blood analysis fulfilled three different criteria of polymyalgia rheumatica (PMR). Therefore, diffuse endocapillary proliferative glomerulonephritis associated with PMR was diagnosed. After low-dose prednisolone (10 mg/day) treatment, the muscle pain disappeared, acute phase reactants decreased and hematuria and proteinuria improved. The renal complication of PMR is rare but important to be considered early in the right clinical context.
ISSN:1664-5510
2296-9705
1664-5510
DOI:10.1159/000345280