Frequency response of vestibular reflexes in neck, back, and lower limb muscles

• Published in: Journal of neurophysiology Vol. 110; no. 8; pp. 1869 - 1881
• Main Authors: Forbes, Patrick A., Dakin, Christopher J., Vardy, Alistair N., Happee, Riender, Siegmund, Gunter P., Schouten, Alfred C., Blouin, Jean-Sébastien
• Format: Journal Article
• Language: English
• Published: United States 01.10.2013
• Subjects: Adult; Afferent Pathways - physiology; Back Muscles - innervation; Back Muscles - physiology; Female; Humans; Lower Extremity - innervation; Lower Extremity - physiology; Male; Middle Aged; Models, Neurological; Motor Neurons - physiology; Neck Muscles - innervation; Neck Muscles - physiology; Reflex; Vestibule, Labyrinth - innervation; Vestibule, Labyrinth - physiology; vestibular reflexes; bandwidth; neural filtering; neck muscles; electrical vestibular stimulation
• ISSN: 0022-3077; 1522-1598; 1522-1598
• DOI: 10.1152/jn.00196.2013

Vestibular pathways form short-latency disynaptic connections with neck motoneurons, whereas they form longer-latency disynaptic and polysynaptic connections with lower limb motoneurons. We quantified frequency responses of vestibular reflexes in neck, back, and lower limb muscles to explain between-muscle differences. Two hypotheses were evaluated: 1) that muscle-specific motor-unit properties influence the bandwidth of vestibular reflexes; and 2) that frequency responses of vestibular reflexes differ between neck, back, and lower limb muscles because of neural filtering. Subjects were exposed to electrical vestibular stimuli over bandwidths of 0–25 and 0–75 Hz while recording activity in sternocleidomastoid, splenius capitis, erector spinae, soleus, and medial gastrocnemius muscles. Coherence between stimulus and muscle activity revealed markedly larger vestibular reflex bandwidths in neck muscles (0–70 Hz) than back (0–15 Hz) or lower limb muscles (0–20 Hz). In addition, vestibular reflexes in back and lower limb muscles undergo low-pass filtering compared with neck-muscle responses, which span a broader dynamic range. These results suggest that the wider bandwidth of head-neck biomechanics requires a vestibular influence on neck-muscle activation across a larger dynamic range than lower limb muscles. A computational model of vestibular afferents and a motoneuron pool indicates that motor-unit properties are not primary contributors to the bandwidth filtering of vestibular reflexes in different muscles. Instead, our experimental findings suggest that pathway-dependent neural filtering, not captured in our model, contributes to these muscle-specific responses. Furthermore, gain-phase discontinuities in the neck-muscle vestibular reflexes provide evidence of destructive interaction between different reflex components, likely via indirect vestibular-motor pathways.