Pathogenic mechanism of Vibrio vulnificus infection

is a fatal, opportunistic human pathogen transmitted through the consumption of raw/undercooked seafood or direct contact. infection progresses rapidly and has severe consequences; some cases may require amputation or result in death. Growing evidence suggests that virulence factors and regulators p...

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Published inFuture microbiology Vol. 18; no. 6; pp. 373 - 383
Main Authors Lu, Kun, Li, Yang, Chen, Rui, Yang, Hua, Wang, Yong, Xiong, Wei, Xu, Fang, Yuan, Qijun, Liang, Haihui, Xiao, Xian, Huang, Renqiang, Chen, Zhipeng, Tian, Chunou, Wang, Songqing
Format Journal Article
LanguageEnglish
Published England 01.04.2023
Subjects
Humans
Vibrio Infections
Vibrio vulnificus
Virulence
Virulence Factors
Vibrio vulnificus
host resistance
iron uptake
cell injury
virulence regulation
cytotoxicity
immune responses
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Summary:is a fatal, opportunistic human pathogen transmitted through the consumption of raw/undercooked seafood or direct contact. infection progresses rapidly and has severe consequences; some cases may require amputation or result in death. Growing evidence suggests that virulence factors and regulators play a large role in disease progression, involving host resistance, cellular damage, iron acquisition, virulence regulation and host immune responses. Its disease mechanism remains largely undefined. Further evaluation of pathogenic mechanisms is important for selecting appropriate measures to prevent and treat infection. In this review, the possible pathogenesis of infection is described to provide a reference for treatment and prevention.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:1746-0913
1746-0921
DOI:10.2217/fmb-2022-0243