Parallel line analysis: multifunctional software for the biomedical sciences

• Published in: Computer methods and programs in biomedicine Vol. 33; no. 2; pp. 95 - 105
• Main Authors: Swank, P.R., Lewis, M.L., Damron, K.L., Morrison, D.R.
• Format: Journal Article
• Language: English
• Published: Legacy CDMS Elsevier Ireland Ltd 01.10.1990
• Subjects: ANOVA; Bioassay; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Life Sciences (General); Mathematical Computing; Parallel line analysis; Programming Languages; Software; Software Design; Space life sciences; User-Computer Interface; Parallel line analysis; ANOVA; Bioassay; Nasa Discipline Cell Biology; Nasa Center Jsc; NASA Center JSC; NASA Discipline Cell Biology
• ISSN: 0169-2607; 1872-7565
• DOI: 10.1016/0169-2607(90)90066-I

An easy to use, interactive FORTRAN program for analyzing the results of parallel line assays is described. The program is menu driven and consists of five major components: data entry, data editing, manual analysis, manual plotting, and automatic analysis and plotting. Data can be entered from the terminal or from previously created data files. The data editing portion of the program is used to inspect and modify data and to statistically identify outliers. The manual analysis component is used to test the assumptions necessary for parallel line assays using analysis of covariance techniques and to determine potency ratios with confidence limits. The manual plotting component provides a graphic display of the data on the terminal screen or on a standard line printer. The automatic portion runs through multiple analyses without operator input. Data may be saved in a special file to expedite input at a future time.