Sertraline-Induced Hypoglycemia in Drug-Induced Liver Injury

Sertraline, a selective serotonin reuptake inhibitor, is a medication recommended as a third line treatment of cholestatic liver injury pruritis. We report a case of a young male who developed liver injury secondary to self-administration of anabolic steroids and who complained of persistent pruriti...

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Published inHospital pharmacy (Philadelphia) Vol. 59; no. 5; pp. 529 - 531
Main Authors Mikhael, Elio, Slim, Rita, El Helou, Santa, Amer, Lamis, Khanfour, Melissa, Yaghi, César
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.10.2024
Subjects
drug-induced liver injury
medication safety
selective serotonin reuptake inhibitors
hypoglycemia
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Summary:Sertraline, a selective serotonin reuptake inhibitor, is a medication recommended as a third line treatment of cholestatic liver injury pruritis. We report a case of a young male who developed liver injury secondary to self-administration of anabolic steroids and who complained of persistent pruritis leading to a treatment by sertraline. Two days later, the patient was admitted to the hospital with a severe hypoglycemia, while the liver function tests were in amelioration. Clinical and biological evaluation were in favor of sertraline-induced hypoglycemia, a side effect rarely reported in non-diabetic patients, and in the context of hepatic injury.
Bibliography:ObjectType-Case Study-2
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ISSN:0018-5787
1945-1253
DOI:10.1177/00185787241242767