Risk Factors Associated With Distress Among Postoperative Patients in an Academic Gynecologic Oncology Practice

• Published in: Journal of the National Comprehensive Cancer Network Vol. 22; no. 2; p. 91
• Main Authors: Gross, Maya E, Sobecki, Janelle N, Park, Chan, Yu, Menggang, Wallace, Sumer K
• Format: Journal Article
• Language: English
• Published: United States 01.03.2024
• Subjects: Female; Genital Neoplasms, Female - complications; Genital Neoplasms, Female - surgery; Humans; Neoplasms - complications; Quality of Life; Retrospective Studies; Risk Factors; Stress, Psychological - epidemiology; Stress, Psychological - etiology; Stress, Psychological - psychology; Surveys and Questionnaires
• ISSN: 1540-1413
• DOI: 10.6004/jnccn.2023.7093

Distress among gynecologic oncology patients correlates with poor clinical outcomes and decreased quality of life. The purpose of this study was to determine risk factors for elevated NCCN Distress Thermometer (DT) results among postoperative gynecologic oncology patients. We performed a retrospective chart review of all postoperative visits over a 5-year period. NCCN DT results were analyzed as both discretized values (DT ≤3 = low distress; DT 4-8 = moderate distress; DT ≥9 = high distress) and continuous variables. Patients with a DT score ≥4 were referred to social work. Univariate and multivariate regression analyses were performed to compare NCCN DT results with clinical and sociodemographic variables. Statistical significance was P<.05. In total, 1,795 NCCN DT results were included, with uterine (37.72%) being the most common disease site. Benign pathology was known prior to completion of the NCCN DT in 13.15% of patients. Most patients (71.75%) endorsed low levels of distress. Moderate/High levels of distress were reported by 28.25% of patients. Increasing levels of distress were significantly associated with younger age (P=.006), history of depression (P≤.001), status as a current smoker (P=.028), and history of asthma (P=.041). Knowledge of benign pathology was associated with low levels of distress (P=.002). Procedure type and disease site were not associated with distress. More than one-fourth of postoperative patients in a gynecologic oncology practice reported moderate or high distress. Distress was highest among those with malignancy regardless of disease site or surgical intervention. Benign pathology correlated with decreased distress. Identified associations with distress provide opportunities for prevention, early intervention, and tailored counseling.