Effects of Indocyanine Green (ICG) Imaging-Assisted Cholecystectomy on Intraoperative and Postoperative Complications: A meta-Analysis

• Published in: Surgical innovation Vol. 31; no. 4; p. 362
• Main Authors: Tang, Yuhong, Liu, Renjie, Liu, Huanxiang, Peng, Rui, Su, Bingbing, Tu, Daoyuan, Wang, Shunyi, Chen, Chen, Jiang, Guoqing, Jin, Shengjie, Cao, Jun, Zhang, Chi, Bai, Dousheng
• Format: Journal Article
• Language: English
• Published: United States 01.08.2024
• Subjects: Cholecystectomy - adverse effects; Cholecystectomy - methods; Coloring Agents; Humans; Indocyanine Green; Intraoperative Complications - prevention & control; Optical Imaging - methods; Postoperative Complications - epidemiology; Postoperative Complications - prevention & control; Surgery, Computer-Assisted - methods; intraoperative complications; postoperative complications; cholecystectomy; indocyanine green; near-infraredfluorescence
• ISSN: 1553-3514
• DOI: 10.1177/15533506241246335

Accurate recognition of Calot's triangle during cholecystectomy is important in preventing intraoperative and postoperative complications. The use of indocyanine green (ICG) fluorescence imaging has become increasingly prevalent in cholecystectomy procedures. Our study aimed to evaluate the specific effects of ICG-assisted imaging in reducing complications. A comprehensive search of databases including PubMed, Web of Science, Europe PMC, and WANFANGH DATA was conducted to identify relevant articles up to July 5, 2023. Review Manager 5.3 software was applied to statistical analysis. Our meta-analysis of 14 studies involving 3576 patients compared the ICG group (1351 patients) to the control group (2225 patients). The ICG group had a lower incidence of postoperative complications (4.78% vs 7.25%; RR .71; 95%CI: .54-.95; = .02). Bile leakage was significantly reduced in the ICG group (.43% vs 2.02%; RR = .27; 95%CI: .12-.62; I = 0; = .002), and they also had a lower bile duct drainage rate (24.8% vs 31.8% RR = .64, 95% CI: .44-.91, = .01). Intraoperative complexes showed no statistically significant difference between the 2 groups (1.16% vs 9.24%; RR .17; 95%CI .03-1.02), but the incidence of intraoperative bleeding is lower in the ICG group. ICG fluorescence imaging-assisted cholecystectomy was associated with a range of benefits, including a lower incidence of postoperative complications, decreased rates of bile leakage, reduced bile duct drainage, fewer intraoperative complications, and reduced intraoperative bleeding.