Maternal and fetal exposure to metal (loid)s, maternal nutrition status, and impact on prenatal growth in an energy rich zone and an urban area along the Persian Gulf

• Published in: Environmental pollution (1987) Vol. 309; p. 119779
• Main Authors: Khalili Doroodzani, Atefeh, Dobaradaran, Sina, Zarei, Sara, Raeisi, Alireza, Mahmoodi, Marzieh, Rahmani, Elham, Nabipour, Iraj, Saeedi, Reza, Mahmudpour, Mehdi, Akbarzadeh, Samad, Keshtkar, Mozhgan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.09.2022
• Subjects: Cord blood; Dietary habit; Environmental Monitoring; Female; Fetal development; Heavy metal; Humans; Indian Ocean; Infant, Newborn; Lead; Maternal blood; Metals, Heavy - analysis; Nutritional Status; Pregnancy; Risk Assessment; Transplacental transfer; Indian Ocean; Maternal blood; Fetal development; Cord blood; Dietary habit; Transplacental transfer; Heavy metal
• ISSN: 0269-7491; 1873-6424
• DOI: 10.1016/j.envpol.2022.119779

The main purposes of the study were to determine whether maternal and cord blood (MB and CB) levels of metal (loid)s (MLs) are different between industrial and urban areas. Subjects were derived from the petrochemical and gas area (PGA) of Asaluyeh County and the urban area (UA) of Bushehr County in Iran. Adjusted models revealed significant differences between the PGA and UA for maternal Fe, Cu, Mg, Cd, Zn, Ni, V and Pb levels, likewise cord Cu, V, Pb and Ni levels, which were higher in the PGA. Unadjusted models revealed there were decreases in neonatal weight and head circumference by 16.550 g and 0.059 cm, respectively for each Ln unit increase in maternal Cr levels. The mean blood levels of MLs significantly associated with food consumption frequency. The MLs were detected at higher levels in the body's fetuses and their mothers who resided in the PGA than those from the UA. So, the fetuses of mothers living in an industrial areas may be at higher risk from anthropometric measures. The impact of prenatal exposure to MLs on prenatal growth should be considered for better understanding in the further studies. [Display omitted] •Maternal and fetal metal (loid) (ML) level compared between industrial and urban area.•Mother-fetuses in the industrial area exposed to MLs higher than urban area.•Fe, Mg, and Zn had the highest levels respectively in all samples in both areas.•Transplacental transfer of MLs from mother to fetus via cord blood was observed.•Increase in maternal Cr associated with lower birth weight and head circumference.