Mixed lymphocyte cultures (MLC) and acute pancreatitis after renal transplantation

MLC was performed preoperatively in 35 out of 57 candidates for renal transplantation. Three patients developed acute pancreatitis in the early postoperative stage, 2 of them died. In these three cases MLC revealed complete non-reactivity of the recipient lymphocytes, compared with the donor as well...

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Bibliographic Details
Published inInternational urology and nephrology Vol. 13; no. 4; p. 391
Main Authors Járay, J, Perner, F, Alföldy, F, Onody, K
Format Journal Article
LanguageEnglish
Published Netherlands 1981
Subjects
Acute Disease
Adult
Female
Humans
Kidney Transplantation
Lymphocyte Culture Test, Mixed
Male
Middle Aged
Pancreatitis - etiology
Pancreatitis - immunology
Postoperative Complications
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Summary:MLC was performed preoperatively in 35 out of 57 candidates for renal transplantation. Three patients developed acute pancreatitis in the early postoperative stage, 2 of them died. In these three cases MLC revealed complete non-reactivity of the recipient lymphocytes, compared with the donor as well as with the positive control lymphocytes. None of the other patients showed this phenomenon and none of them developed acute pancreatitis. It is suggested that the recipient's immune responsiveness may be involved in the aetiology of the production of acute pancreatitis after renal transplantation.
ISSN:0301-1623
DOI:10.1007/bf02081941