Reference intervals of serum folate and vitamin B12 developed from data of healthy subjects

In this study the reference intervals for folate and vitamin B12 were estimated according to the National Committee for Clinical Laboratory Standards Approved Guideline C28-A and International Federation of Clinical Chemistry recommendations. The study included 155 women and 124 men between ages 18–...

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Published inAccreditation and quality assurance Vol. 5; no. 9; pp. 383 - 387
Main Authors TANYALCIN, Tijen, ASIAN, Diler, KURTULMUS, Yusuf, GÖKALP, Nalan, KUMANLIOGLU, Kamil
Format Conference Proceeding Journal Article
LanguageEnglish
Published Heidelberg Springer 01.09.2000
Berlin Springer Nature B.V
Subjects
Biological and medical sciences
Cyanocobalamin
General aspects
Intervals
Medical sciences
Men
Women
Quality assurance
Quality criterion
Q factor
Clinical biology
Vitamin deficiency
Cyanocobalamin
Folate
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Summary:In this study the reference intervals for folate and vitamin B12 were estimated according to the National Committee for Clinical Laboratory Standards Approved Guideline C28-A and International Federation of Clinical Chemistry recommendations. The study included 155 women and 124 men between ages 18–40. The health status was confirmed by history, physical examination and a questionnaire. The central 95% reference intervals of serum folate and vitamin B12 for women, determined non-parametrically, were found to be 3.9–18.1 ng/ml and 101–666.7 pg/ml, respectively. The reference values of serum folate and vitamin B12 for men were also found to be 2,5–17.6 ng/ml and 100–699.57 pg/ml, respectively. We did not observe subclass differences between females and males.
ISSN:0949-1775
1432-0517
DOI:10.1007/s007690000195