Immunohistochemical analysis of cyclin E in Wilms tumors
We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases on lungs and one case of normal renal tissue. Correlation of semiquantitatively scored cyclin E levels with histopathological parameters was performed for all cases. Our findings suggest that diffuse expression of cyclin E is a...
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Published in | Acta veterinaria (Beograd) Vol. 57; no. 5-6; pp. 453 - 464 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
2007
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Subjects | |
Online Access | Get full text |
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Summary: | We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases on lungs and one case of normal renal tissue. Correlation of semiquantitatively scored cyclin E levels with histopathological parameters was performed for all cases. Our findings suggest that diffuse expression of cyclin E is associated with the prognostic group and tumor stage. Also, cyclin E expression is more pronounced in the blastemal component than in the epithelial component. Diffuse expression of cyclin E is associated with an unfavourable outcome of Wilms tumor. |
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Bibliography: | L70 L73 COBISS.SR-ID 3254530 |
ISSN: | 0567-8315 1820-7448 |
DOI: | 10.2298/AVB0706453R |