Quantitative Analysis of Azodicarbonamide in Insulation Layers of Extruded Cables by HPLC–UV Detection

• Published in: Journal of analysis and testing Vol. 5; no. 4; pp. 370 - 378
• Main Authors: Shen, Sensen, Chang, Cuilan, Shen, Chenbo, Xu, Harvey, Miao, Shawn, Wills, Scott
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.12.2021
• Subjects: Analytical Chemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Monitoring/Environmental Analysis; Original Paper; Azodicarbonamide; Cable insulation layers; Total dissolution methodology; HPLC–UV
• ISSN: 2096-241X; 2509-4696
• DOI: 10.1007/s41664-021-00154-3

Azodicarbonamide (ADC), which has been abundantly used in the creation of foamed plastics as a blowing and foaming agent, has attracted more and more attention in recent years due to the health risks associated with its consumption. ADC is actually on the REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulation Candidate List of Substances of Very High Concern, and the residual content in products needs to be confirmed by the end users according to regulations. Therefore, the determination and monitoring of ADC in plastic products is necessary and crucial not only for the growth of ADC global market but also for the health of the public. In this work, a quantitative method for ADC in insulation layers of cables was developed by using optimized total dissolution methodology (TDM) for sample preparation followed by HPLC under HILIC conditions with UV absorbance detection. The linear range of this method was 6–600 μg·g −1 , and the limit of detection (LOD) and limit of quantitation (LOQ) were 0.94 and 3.1 μg·g −1 in solution, respectively. The method has good recovery and precision, and is easy to operate. It meets the needs of the industry and is conducive to the growth of ADC global market. This method is expected to be applicable to ADC quantitation in other polyolefin products.