Feasibility of Magnetic Seeds for Preoperative Localization of Axillary Lymph Nodes in Breast Cancer Treatment

• Published in: American journal of roentgenology (1976) Vol. 213; no. 4; pp. 953 - 957
• Main Authors: Greenwood, Heather I, Wong, Jasmine M, Mukhtar, Rita A, Alvarado, Michael D, Price, Elissa R
• Format: Journal Article
• Language: English
• Published: United States 01.10.2019
• Subjects: Adult; Aged; Axilla - diagnostic imaging; Axilla - pathology; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - pathology; Feasibility Studies; Female; Fiducial Markers; Humans; Lymphatic Metastasis - diagnostic imaging; Lymphatic Metastasis - pathology; Magnetic Resonance Imaging; Magnetics; Middle Aged; Preoperative Care; Retrospective Studies; localization; breast cancer; Magseed; axilla; ultrasound
• ISSN: 0361-803X; 1546-3141
• DOI: 10.2214/AJR.19.21378

The objective of this study was to evaluate the feasibility of using a magnetic seed system for preoperative localization of axillary lymph nodes in patients with breast cancer. We performed a retrospective analysis that included patients with breast cancer who underwent preoperative magnetic seed localization of axillary lymph nodes at our institution between January 1, 2017, and January 1, 2019. Magseed (Endomag) is a nonradioactive inducible magnetic seed that is induced to become a magnet when under the influence of its detector in the operating room. Clinical history, prior axillary sampling and clip placement, and procedure details and surgical outcomes were determined from a search of our PACS and electronic medical records. Thirty-five patients (34 women and one man) composed our study cohort. The mean patient age was 56 years (range, 32-78 years). One patient underwent two separate consecutive localizations for two separate operations, and another patient had bilateral lesions, for a total of 37 axillary lymph node localizations. One case of seed misplacement occurred during the ultrasound-guided localization procedure, resulting in immediate placement of a second seed, for a total of 38 Magseeds placed. All seeds were placed under ultrasound guidance. The mean number of days from seed placement to surgery was 5 days (range, 0-31 days). Thirty-seven of 38 Magseeds (97%) were documented to be successfully retrieved in the operating room. Magseed localization appears to be a safe, nonradioactive way to accurately localize axillary lymph nodes preoperatively.