Stimulation of cellular ingestion by basic proteins in vitro

• Published in: British journal of cancer Vol. 33; no. 4; pp. 392 - 399
• Main Authors: Westwood, F R, Longstaff, E
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.04.1976
• Subjects: Animals; Benzopyrenes; Carbon; Cells, Cultured; Female; Fibroblasts - drug effects; Fibroblasts - physiology; Fibroblasts - ultrastructure; Histones - pharmacology; L Cells (Cell Line); Macrophages - drug effects; Macrophages - physiology; Male; Neoplasms - chemically induced; Peptides - pharmacology; Phagocytosis - drug effects; Polylysine - pharmacology; Rats; Serum Albumin, Bovine - pharmacology

The ingestion of carbon and benzpyrene particles in vitro by rat peritoneal macrophages, baby hamster kidney fibroblasts (BHK-21) and mouse L-cells has been shown to be significantly stimulated by the inclusion of histone or polylysine in the culture medium. Parallel studies using methylated bovine...