Single-step replication of a highly integrated PDMS optofluidic analysis system

Micromilling is a promising technology for the fabrication of surface profiles with optical quality. We present a highly integrated optofluidic system made of polydimethylsiloxane (PDMS). The system is replicated in a single-step process from a micromilled polymethyl methacrylate master mold. It alr...

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Bibliographic Details
Published inApplied optics. Optical technology and biomedical optics Vol. 49; no. 22; p. 4326
Main Authors Amberg, Martin, Stoebenau, Sebastian, Sinzinger, Stefan
Format Journal Article
LanguageEnglish
Published United States 01.08.2010
Subjects
Algorithms
Dimethylpolysiloxanes - chemistry
Electrodes
Equipment Design
Lasers
Microelectrodes
Microfluidics
Optical Tweezers
Optics and Photonics
Polymethyl Methacrylate - chemistry
Surface Properties
Temperature
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Summary:Micromilling is a promising technology for the fabrication of surface profiles with optical quality. We present a highly integrated optofluidic system made of polydimethylsiloxane (PDMS). The system is replicated in a single-step process from a micromilled polymethyl methacrylate master mold. It already includes the reservoirs, the channel system, as well as the optical interconnect surfaces for high numerical aperture objectives. We demonstrate the potential of this approach by laser-based three-dimensional optical manipulation within the replicated system. To our knowledge, this is the first time that a PDMS membrane is used as a well-defined channel wall for an optical trapping setup.
ISSN:2155-3165
DOI:10.1364/AO.49.004326