Anatomical characterization of central, apical and minimal corneal thickness

• Published in: International journal of ophthalmology Vol. 7; no. 4; pp. 668 - 672
• Main Author: Federico Saenz-Frances Martha Cecilia Bermúdez-Vallecilla Lara Borrego-Sanz Luis Jaez J osé Marìa Martinez-de-la-Casa Laura Morales-Fernandez Enrique Santos-Bueso Julián Garcia-Sanchez Julián Garcia-Feijoo
• Format: Journal Article
• Language: English
• Published: China International Journal of Ophthalmology Press 18.08.2014; Press of International Journal of Ophthalmology (IJO PRESS)
• Subjects: acuity; anatomy; apical; Clinical Research; corneal; corneal thickness; gender; glaucoma; inferior; intraocular; locate; multivariate; sectional; anatomy; corneal thickness; glaucoma
• ISSN: 2222-3959; 2227-4898
• DOI: 10.3980/j.issn.2222-3959.2014.04.15

·AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness(pupil center) in relation to the corneal apex.·METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex(AT),minimum corneal thickness(MT) and corneal thickness at the pupil center(PT) were determined using the pentacam. Distances from the corneal apex to MT(MD)and PT(PD) were calculated and their quadrant position(taking the corneal apex as the reference) determined:point of minimum thickness(MC) and point of central thickness(PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume(determined using the Pentacam)and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.·RESULTS: MT was located at a mean distance of 0.909 mm from the apex(79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume(B =-0.024; 95% CI:-0.043 to-0.004). No significant relations were identified in the linear regression model for PD or the multinomial logisticregressions for MC and PC.·CONCLUSION: MT was typically located at the inferiortemporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.