Study of baseline Widal titres in a healthy adult population of Wayanad district, Kerala, India

The Widal test is still widely used in diagnosing typhoid fever in developing countries. Often, specific chemotherapy is administered based on a single Widal test. Interpretation of a single Widal test, in turn, depends on the baseline agglutinin titres among the local population in that area. Hence...

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Bibliographic Details
Published inTropical doctor Vol. 45; no. 1; p. 12
Main Authors Maulingkar, Saleel V, Prakash, R, Harish, P V, Salabha, B
Format Journal Article
LanguageEnglish
Published England 01.01.2015
Subjects
Adult
Agglutination Tests - standards
Cross-Sectional Studies
Developing Countries
Female
Humans
India
Male
Reference Values
Salmonella typhi
Typhoid Fever - blood
Typhoid Fever - diagnosis
India
baseline titre
Salmonella
typhoid
Widal
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Summary:The Widal test is still widely used in diagnosing typhoid fever in developing countries. Often, specific chemotherapy is administered based on a single Widal test. Interpretation of a single Widal test, in turn, depends on the baseline agglutinin titres among the local population in that area. Hence, we aimed to find out the baseline titres in our area. A single blood sample was collected from hospital outpatients with non-infectious diseases, the patients being aged above 18 years and residing in Wayanad district continuously for at least 5 years. The test was performed according to the Widal test kit manufacturer's instructions and interpreted using standard guidelines. The baseline titre for Anti TO, TH, AH and BH agglutinins in our area was found to be 1:40, 1:80, 1:40 and 1:40, respectively.
ISSN:1758-1133
DOI:10.1177/0049475514550237