Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57

The LCK gene encodes a lymphocyte-specific member of the Src family of protein tyrosine kinases. This gene was previously assigned to human chromosome region 1p35-->p32 by isotopic in situ hybridization. We report here its more refined localization to bands 1p35-->p34.3 by fluorescence in situ...

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Bibliographic Details
Published inCytogenetics and cell genetics Vol. 67; no. 3; p. 187
Main Authors Volpi, E V, Romani, M, Siniscalco, M
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1994
Subjects
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 1
Genetic Markers
Humans
In Situ Hybridization, Fluorescence
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Lymphocytes
Molecular Sequence Data
Protein-Tyrosine Kinases - genetics
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Summary:The LCK gene encodes a lymphocyte-specific member of the Src family of protein tyrosine kinases. This gene was previously assigned to human chromosome region 1p35-->p32 by isotopic in situ hybridization. We report here its more refined localization to bands 1p35-->p34.3 by fluorescence in situ hybridization on R-banded metaphase chromosomes and its mapping relative to the reference marker pYNZ2 (D1S57).
ISSN:0301-0171
DOI:10.1159/000133819