Acute Coronary Syndrome in Indian Subcontinent Patients Residing in the Middle East: Results From Gulf Registry of Acute Coronary Events II

• Published in: Angiology Vol. 66; no. 9; p. 818
• Main Authors: Panduranga, Prashanth, Sulaiman, Kadhim J, Al-Zakwani, Ibrahim, Alhabib, Khalid F, Hersi, Ahmad, Suwaidi, Jassim Al, Alsheikh-Ali, Alawi A, Almahmeed, Wael, Saif, Shukri Al, Al-Faleh, Hussam, Al-Lawati, Jawad, Asaad, Nidal, Al-Motarreb, Ahmed, Amin, Haitham
• Format: Journal Article
• Language: English
• Published: United States 01.10.2015
• Subjects: Acute Coronary Syndrome - diagnosis; Acute Coronary Syndrome - ethnology; Acute Coronary Syndrome - mortality; Adult; Aged; Arabs; Asian Continental Ancestry Group; Chi-Square Distribution; Female; Health Status Disparities; Hospital Mortality; Hospitalization; Humans; India - ethnology; Logistic Models; Male; Middle Aged; Middle East - epidemiology; Middle East - ethnology; Multivariate Analysis; Odds Ratio; Prognosis; Prospective Studies; Registries; Risk Assessment; Risk Factors; Time Factors; Middle East; India; Middle East; Arabs; acute coronary syndrome; Indian subcontinent; South Asians
• ISSN: 1940-1574
• DOI: 10.1177/0003319714556812

We compared baseline characteristics, clinical presentation, and in-hospital outcomes between Middle Eastern Arabs and Indian subcontinent patients presenting with acute coronary syndrome (ACS). Of the 7930 patients enrolled in Gulf Registry of Acute Coronary Events II (RACE II), 23% (n = 1669) were from the Indian subcontinent. The Indian subcontinent patients, in comparison with the Middle Eastern Arabs, were younger (49 vs 60 years; P < .001), more were males (96% vs 80%; P < .001), had lower proportion of higher Global Registry of Acute Coronary Events risk score (8% vs 27%; P < .001), and less likely to be associated with diabetes (34% vs 42%; P < .001), hypertension (36% vs 51%; P < .001), and hyperlipidemia (29% vs 39%; P < .001) but more likely to be smokers (55% vs 29%; P < .001). After multivariable adjustment, the Middle Eastern Arabs were less likely to be associated with in-hospital congestive heart failure (odds ratio [OR], 0.65; 95% confidence interval [CI]: 0.50-0.86; P = .003) but more likely to be associated with recurrent ischemia (OR 1.33; 95% CI: 1.03-1.71; P = .026) when compared to the Indian subcontinent patients. Despite the baseline differences, there were largely no significant differences in in-hospital outcomes between the Indians and the Middle Eastern Arabs.