Quantitative analysis of brain synaptophysin (p38) in offspring of male rats with chronic morphine intoxication

Cerebral synapses in offspring of male rats treated with morphine for a month before mating were studied using synaptophysin (p38) as a synaptic marker. The content of p38 in the nucleus accumbens, hippocampus, and layers III and V of the somatosensory cortex was below the control, while no signific...

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Published inBulletin of experimental biology and medicine Vol. 129; no. 1; pp. 41 - 43
Main Authors Khrenov, A. I., Belichenko, P. V., Shamakina, I. Yu
Format Journal Article
LanguageEnglish
Published New York Springer Nature B.V 01.01.2000
Subjects
Brain
Rodents
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Summary:Cerebral synapses in offspring of male rats treated with morphine for a month before mating were studied using synaptophysin (p38) as a synaptic marker. The content of p38 in the nucleus accumbens, hippocampus, and layers III and V of the somatosensory cortex was below the control, while no significant changes were found in the motor cortex, caudate nucleus, and ventrolateral thalamic nuclei.[PUBLICATION ABSTRACT]
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433864